Effects of Intravenous Magnesium Sulfate and Lidocaine on Hemodynamic Responses Following Direct Laryngoscopy and Intubation in Elective Surgery Patients.

Dhruti Prasad Parida; Chandrasekhar Behera; Nihar Ranjan Tripathy

Volume : VIII, Issue : VII, July - 2019

Effects of Intravenous Magnesium Sulfate and Lidocaine on Hemodynamic Responses Following Direct Laryngoscopy and Intubation in Elective Surgery Patients.

Dhruti Prasad Parida, Chandrasekhar Behera, Nihar Ranjan Tripathy

Abstract :

Background and objective: Laryngoscopy and Intubation lead to hemodynamic changes like Increase in heart rate, arterial blood pressure, and arrhythmia. Several medical methods have been suggested attenuate this response. This study corresponds to the intravenous administration of lidocaine and magnesium sulfate on unwanted hemodynamic response following laryngoscopy and intubation in elective surgery conditions. Materials and Methods: This randomized, double–blind chemical trial conducted on Sixty ASA I and II candidates who received magnesium sulfate 30mg/Kg and lidocaine (1.5mg /kg) randomly before intubation. Values of systolic blood pressure, diastolic blood pressure, mean arterial pressure, and heart rate was recorded in both groups in 1st to 5th minutes following administration and compared with baseline values. Results: In the magnesium group, the increase in systolic blood pressure occurred in the 1st minute, which was significant. The increase in diastolic blood pressure was significant in Lidocaine group in the 1st minute. The mean arterial pressure showed lower values in 1st and 2nd minutes, and mean heart rate was lower in 1st minutes in Magnesium group with statistical significance. Conclusion: Magnesium sulfate is comparatively more effective in controlling hemodynamics than Lidocaine attenuating pressure response to laryngoscopy and intubation.