Epidermolysis Bullosa Dytrophica (EBD)-Case report

Likhitha Marni; N.Akshita; Dr G. Ramya Bala Prabha; Sharadha Srikanth; Dr.K Abbulu

Volume : VIII, Issue : IV, April - 2019

Epidermolysis Bullosa Dytrophica (EBD)-Case report

Likhitha Marni, N. Akshita, Dr G. Ramya Bala Prabha, Sharadha Srikanth, Dr. K Abbulu

Abstract :

Introduction: Epidermolysis bullosa is a group of rare genetic conditions that cause the skin to become very fragile, delicate and vulnerable to develop blisters easily. Blisters, lesions, and skin erosions form in response to minor injury or friction, such as rubbing or scratching. The signs and symptoms can vary widely among affected people.The definitive diagnosis of inherited EB is made with transmission electron microscopy (TEM), immunofluorescence antigen mapping (IF), and EB related monoclonal antibody testing as well as mutational analysis. Discussion: A 20 years old female with a history of erythema and fluid filled blisters on fingers since birth, developed spontaneous bullae that gradually became itchier. She was admitted to dermatology ward in tertiary care hospital. It was observed that she developed multiple blisters along with few tender blisters on the extremities of her body. These fluid filled lesions began to smell from the past 15 days as they developed all over both legs and arms associated with itching. She also developed excoriated lesions, filled with pus. These pus filled lesions ruptured after a couple of days. Her nails were observed to be ridging and her teeth were also found to be discolored. During the hospital administration, patient was managed symptomatically for itching, inflammation, and allergy. Conclusion: EBD is a rare inherited disease that affects the skin and other organs. epidermolysis bullosa dystrophica is seen in people with fragile skin and people who are highly susceptible to blisters.The basic care for all EB patients are avoidance of blistering and prevention of secondary infection.