EVALUATION OF ANXIOLYTIC ACTIVITY OF CANANGA ODORATA LEAVES IN SWISS ALBINO MICE

Dr Yasmeen A Maniyar; Dr Siddarameshwar C B

Volume : VII, Issue : VIII, August - 2018

EVALUATION OF ANXIOLYTIC ACTIVITY OF CANANGA ODORATA LEAVES IN SWISS ALBINO MICE

Dr Yasmeen A Maniyar, Dr Siddarameshwar C B

Abstract :

CanangaOdorataplant is on one of the most commonly used plants in aromatherapy.This study intends to demonstrate anxiolytic action ofEthanolicExtract ofCanangaOdorataLeaves (EECOL) in Swiss Albino Mice using Elevated plus maze .Animals were divided into 5 groups with 6 animals (n=6) each. Diazepam was used as standard drug. EECOL was given by oral feeding for test groups at doses of 100mg, 200mg, and 400mg/kg respectively. Animals were placed in elevated maze and allowed to move freely for 300seconds. Entry into the open and closed arms, time spent in open and closed arm were noted.

It was observed that the number ofentries and time spent by EECOL treatedanimals in the open arm increased significantly compared to control group. The study suggests that EECOL has anxiolytic activity on Swiss Albino Mice