Evaluation of autologous platelet rich fibrin as therapeutic modality in chronic non healing leg ulcer.

DR YOGENDRA P CHIDRAWAR; DR ANIL V DAROKAR; DR BHUSHAN J TELHURE; DR ANKUR B CHAWLA

Volume : VII, Issue : VIII, August - 2018

Evaluation of autologous platelet rich fibrin as therapeutic modality in chronic non healing leg ulcer.

Dr Yogendra P Chidrawar, Dr Anil V Darokar, Dr Bhushan J Telhure, Dr Ankur B Chawla

Abstract :

BACKGROUND: Chronic leg ulcers occupy a significant number of OPD and IPD patients. Currently, Platelet Rich Fiin (PRF) is being used in reconstructive, cosmetic and dermatologic surgery to improve tissue healing. Wound healing by application of an autologous platelet memane is a safe, easy and inexpensive modality to treat chronic ulcers. Our aim was to study its efficacy in leg ulcers.

METHODS: 24 patients with 24 ulcers were included in the study. Patients were subjected to once weekly sitting of PRFM for a period of 4 weeks and healing of the ulcer was assessed. Area and volume were calculated and photographs were taken. Final assessment of reduction in the size of the ulcer was determined in percentage

RESULTS: A total of 24 patients with 24 ulcers were included in the study. According to the etiology, there were 6 patients (25%) of Hansen’s disease, 5 patients (20.83%) of diabetic foot ulcer, 3 patients (12.5%) of venous ulcers, 4 patients (16.66%) of vascultis and 6 patients (25%) of traumatic ulcer. At the end of four sessions, 4 week follow–up, 1 patient (4.16%) showed reduction by 100%, 12 (50%) patients showed reduction in ulcer size by 70%, 8 (33.33%) showed reduction by 50% and 3 (12.5%) showed reduction by 30%.

CONCLUSION: PRFM is a safe, cost effective modality available even in small setup hospitals without requirement of many skills. Despite the various etiological factors of chronic leg ulcers, it can be very well applied in any type of ulcer without any side–effect.