EVALUATION OF FACTORS INFLUENCING SURVIVAL AMONGST PATIENTS ON MAINTAINENCE HAEMODIALYSIS

Dr Brijesh Verma; Dr Nitin Nahar

Volume : VIII, Issue : XII, December - 2019

EVALUATION OF FACTORS INFLUENCING SURVIVAL AMONGST PATIENTS ON MAINTAINENCE HAEMODIALYSIS

Dr Brijesh Verma, Dr Nitin Nahar

Abstract :

Introduction– Survival of patients on hemodialysis depend upon multiple risk factors. Common independent predictors of survival are age, race, serum albumin at the start of dialysis, activity level at the start of dialysis, and presence of certain comorbidities such as heart failure and cancer. The present study was thus conducted to assess the factors influencing survival among patients on maintenance haemodialysis. Methodology– The study was conducted as a prospective study in Department of Medicine, Gandhi Medical College and associated Hamidia Hospital, Bhopal for a period of 2 year on 100 patients with ESRD. All adult patients with ESRD who survived first 3 months on maintenance hemodialysis and consenting for the study were included in the study. Detailed data pertaining to causes and risk factors of CKD, clinical conditions of patients at initiation and last session of dialysis and treatments given was obtained and entered in questionnaire. Patients were followed up at 4 monthly interval for a total duration of 2 years and survival was noted. Data was compiled using Ms Excel and analysed using SPSS software version 20. Results– Overall mortality in present study was documented to be 34% and mean survival time was observed to be 2.4 (CI–2.248–2.605) years. Mortality was significantly higher in patients with hypertension, severe anemia, hypalbuminemia, hypocalcemia, hyperphosphatemia, hypercholesterolemia, diabetic, high grade urea and creatinine, hypernatremia, hyperkalemia, diabetes and infections (p<0.05). Conclusion– The present study documented overall mortality of 34% and the mean survival time was 2.4 (CI–2.248–2.605) years following initiation of dialysis.The risk factors associated with increased mortality were hypertension, severe anemia, severely deranged liver, lipid and renal profile (p<0.05). Also diabetes, anemia, infections and hypertension (p<0.05) were poor predictors of survival and were significantly associated with mortality.