FTIR Analysis On Siddha Herbal Drug Valladhi Rasayanam

S.V.L.Nimeshika Devi; M.Navinkumar; M.Ahamed Mohideen

Volume : VIII, Issue : VI, June - 2019

FTIR Analysis On Siddha Herbal Drug Valladhi Rasayanam

S. V. L. Nimeshika Devi, M. Navinkumar, M. Ahamed Mohideen

Abstract :

Background: The Valladhi Rasayanam is a polyherbal drug used for treating vatha diseases,cancer,leprosy,eczema and other skin ulcers. Objectives: To characterize the polyherbal drug Valladhi Rasayanam. Materials and methods: The ingredients such as Semecarpus anacardium,Zingiber officinale,Piper nigrum,Piper longum,Curcuma longa,Carum copticum,Cuminum cyminum,Vernonia anthelmentica,Embelia ribes, Smilax china,Plumbago indica,Sesamum indicum. The drug was prepared as per Siddha literature Dhanuvin Sankira Sindhamani. The drug was analysed under FTIR Spectrum. Results: FTIR charecterization shows the presence of some functional group such as alkane, esters, lactone, aliphatic ketone, carboxylic acid, imine/oxime, aromatics, amine, vinyl ether, tertiary alcohol, primary alcohol, sulfoxide,alkene compounds were in Siddha polyherbal drug Valladhi Rasayanam.This study forms the base for the pharmaceutical analysis of Valladhi Rasayanam which will be followed by safety and efficacy studies later. Conclusion: The instrumental analysis FTIR study for Valladhi Rasayanam shows the presence of functional groups through the stretch and bends which responsible for its functional activity. It shows the presence of alkanes,amines, vinyl ether, alcohol, sulfoxide, lactone and aromatic compounds. It has anti inflammatory,analgesic, anesthetic, sedative, anti hypertensive, auto immune and anti microbial activities. Further researches want to be done in the Valladhi Rasayanam to prove the efficacy and standardization of the drug.