Functional Efficacy of intra articular injection of platelet rich plasma in patients with osteoarthritis of knee

Dr. Vikram Sharma

Volume : VIII, Issue : I, January - 2019

Functional Efficacy of intra articular injection of platelet rich plasma in patients with osteoarthritis of knee

Dr. Vikram Sharma

Abstract :

This study was undertaken to study the efficacy of intraarticular injection of platelet rich plasma in relieving pain and improving function in patients suffering from osteoarthritis of the knee. This is a prospective study of 57 knees. PRP was prepared using standard technique and the intervention was performed as an outpatient procedure. The outcome was determined on the basis of VAS and IKDC score, before the injection and at 6 weeks 12 weeks and 24 weeks. At 6 weeks improvement in IKDC scores was seen with a mean value of 7.0, which was statiscally significant. At 12 weeks, there was statiscally significant improvement in IKDC score with a mean value of 12.2. At 24 weeks again there was improvement in IKDC score with a mean value of 12.6. Clinical improvement was also evident by VAS score as it showed decrease in pain. At 4 weeks VAS score ranged from 16 to 34 mm at 6 weeks and mean score of 26.7 and standard deviation of 8.60766.At 12 weeks VAS score ranged from 18 to 32 mm and mean score of 24.9 and standard deviation of 6.96126. At 24 weeks VAS score ranged from 20 to 30 mm and mean score of 23.6 and standard deviation of 5.62792. At 6 weeks only 14% cases showed excellent, 68% cases showed good and. 18% cases showed fair results. At 12 weeks follow up 16% cases showed excellent, 82% cases showed good and fair results were seen in 2% cases. No case had poor results. At 24 weeks follow up 16% cases showed excellent, 86% cases showed good and 6% cases showed fair results and no case had poor results. Based on the above findings our study does suggest that intra articular injections of PRP do help in relieving pain and improving function in patients with mild to moderate osteoarthritis of knee