Volume : VII, Issue : III, March - 2018

Gastrointestinal Stromal Tumors (GISTs): diagnosis and treatment

Rachid Tanz, Tarik Mahfoud, Bazine Aziz, Mohammed Reda Khmamouch, Choukri El Mhadi, Mehdi Toreis, Abdelmounaim Ait Ali, Hassan Errihani, Mohamed Ichou

Abstract :

 

Gastrointestinal Stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. Their cellular origins are found in cells of Cajal which are responsible of the induction and regulation of peristalsis and smooth muscle (1). GISTs are rare in the soft tissue sarcomas but have particular interest because since the 2000s enormous progress was performed about:

• Nosological identification by molecular biology

• Endoscopic and radiological studies.

• Knowledge of prognostic factors.

 • Development of targeted therapies

 All this has led to a significant improvement of prognosis with a median survival that goes from 12 to 50 months in the metastatic setting.

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Article: Download PDF    DOI : https://www.doi.org/10.36106/paripex  

Cite This Article:

RACHID TANZ, TARIK MAHFOUD, BAZINE AZIZ, MOHAMMED REDA KHMAMOUCH, CHOUKRI EL MHADI, MEHDI TOREIS, ABDELMOUNAIM AIT ALI, HASSAN ERRIHANI, MOHAMED ICHOU, Gastrointestinal Stromal Tumors (GISTs): diagnosis and treatment, PARIPEX‾INDIAN JOURNAL OF RESEARCH : Volume-7 | Issue-3 | March-2018


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