HISTOPATHOLOGICAL PROFILE OF CARCINOMA GALLBLADDER

Ashish Jaiswal; Lalit Choudhary; N S Bhat; K S Shahi

Volume : VIII, Issue : I, January - 2019

HISTOPATHOLOGICAL PROFILE OF CARCINOMA GALLBLADDER

Ashish Jaiswal, Lalit Choudhary, N S Bhat, K S Shahi

Abstract :

Carcinoma gallbladder is one of the most common and aggressive primary hepatobiliary malignancy with poor prognosis, and predominantly affects females and older persons. Most gallbladder carcinomas are adenocarcinomas. Among them, the pancreatobiliary is the most common subtype, followed by intestinal type. Usually in most patients carcinoma gall bladder is diagnosed at advanced stage of the disease because of the poorly defined gall bladder muscularis. Aims: This study was conducted to identifying common histological variant of carcinoma gallbladder at our centre along with analyse of clinical presentation and radiological findings of this disease. Methods: An observational prospective analytic study was done to identify the common histological variants of carcinoma gallbladder at Dr. Sushila Tiwari Govt. hospital attached to GMC Haldwani over a period of 2 years from September 2011 to August 2013. Results: There were total 66 patients registered during this time span for carcinoma gallbladder, out of these, 44 were female and 22 were male. Single predominant age group was 61–70 years (33.33%) with mean age 53.56 ±12.62 years. Abdominal lump and pain were most common presenting complaints. Adenocarcinoma was most dominant variants found in more than 90% of patients. Conclusions: Reporting of every specimen must be encouraged to identify true incidence of various histological variants, which helps future clinical researches on histology based targeted therapy.