Intrathecally Buprenorphine With 0.5% Heavy Bupivacaine for Postoperative Analgesia in Cesarean Section: A randomised control trial.

Dr. Mohammed Irfan; Dr. Mohammed Mishal; Dr. S. P. Chittora

Volume : IX, Issue : III, March - 2020

Intrathecally Buprenorphine With 0.5% Heavy Bupivacaine for Postoperative Analgesia in Cesarean Section: A randomised control trial.

Dr. Mohammed Irfan, Dr. Mohammed Mishal, Dr. S. P. Chittora

Abstract :

This study was aimed to evaluate the effect of addition of intrathecal Buprenorphine to Bupivacaine heavy 0.5% on post operative analgesia in caesarian sections and the side effects associated with use of Buprenorphine. Method: Sixty patients posted for elective caesarian sections were randomly divided in two groups of 30 patients each. Patient received either 1.7 ml 0.5% Bupivacaine with + 0.3ml NS (Group A) or 1.7 ml 0.5% Bupivacaine with 90 mcg (0.3ml) buprenorphine (Group B) intrathecally. Results: Onset of analgesia was 3.2±0.2 min in group A while in group B 1.9±.1.42 min. Duration of postoperative analgesia was significantly prolonged in Group B (661.63±96.33min) than Group A (180.60±20.86min). Addition of buprenorphine 90μg to intrathecal bupivacaine prolonged the duration of postoperative analgesia after LSCS without effect of on neonatal Apgar score and with minimal maternal side effect.