Nebulizer Versus Metered Dose Inhalers In The Management Of Acute Exacerbation Of Asthma In Paediatric Emergency Room.

Dr. Sundram; Dr. Sathish Narayanan

Volume : VIII, Issue : I, January - 2019

Nebulizer Versus Metered Dose Inhalers In The Management Of Acute Exacerbation Of Asthma In Paediatric Emergency Room.

Dr. Sundram, Dr. Sathish Narayanan

Abstract :

AIMS AND OBJECTIVES: The aim of the study is to compare the efficacy of aerosolized beta 2 agonists delivered via a nebulizer versus a metered dose inhaler for the treatment of acute exacerbation in pediatric age groups. STUDY DESIGN: a) Inclusion criteria: – Children aged between of 3 to 14 years, who had been diagnosed as having onchial asthma and attending Paediatric Emergency room with acute exacerbation. b) Exclusion criteria: – Age below 3years – Bronchiolitis. – Clinical/Radiological Pneumonia – Chronic pulmonary diseases ( cystic fiosis, pulmonary tuberculosis, emphysema, etc ) – Pulmonary and/or cardiac congenital malformations. – Foreign body aspirations. – Children of parents who are not willing to participate in the study. METHODOLOGY: Study group: Paediatric age group( age 3 to 14 years) Sample size: 80 subjects Study design: Randomized prospective study Children aged between 3–14 years ought to Paediatric ER with acute exacerbation of asthma aged between 3 to 14 years, will be randomized into 2 equal groups to receive aerosolized beta 2 agonist via nebulizer (group 1) and via metered dose inhaler (group 2). Clinical assessment of severity will be assessed based on Sensorium, Heart rate, Respiratory rate, Retractions, oxygen saturation, wheeze severity and air entry. The response to therapy will be assessed after half an hour, 1 hour, 1 and half hour and 2 hours. Outcome of therapy in these two groups will be assessed based on improvement in the respiratory distress, sensorium, air entry, oxygen saturation and the need for admission after 2 hours of therapy and will be compared between them. PLAN FOR STATISTICAL ANALYSIS: Descriptive statistics using SPSS software