Prevalence and Antibiotic Susceptibility Pattern of Pseudomonas aeruginosa Isolates from Wound infections

N.ABY CHANDY; DR KALYANI M

Volume : VIII, Issue : XI, November - 2019

Prevalence and Antibiotic Susceptibility Pattern of Pseudomonas aeruginosa Isolates from Wound infections

N. Aby Chandy, Dr Kalyani M

Abstract :

INTRODUCTION Wound infections are the most common sources of morbidity worldwide. According to recent studies conducted it has come to light that various wound infectons are caused by Pseeudomonas aeruginosa than Staphylococcus aureus. Pseudomonas aeruginosa is one of the most important microorganisms that cause clinical problems resulting from high resistance to antimicrobial agents. Therefore the present study was undertaken to find out the antibiotic susceptibility patterns of P.aeruginosa from various specimens of wound infections. AIM AND OBJECTIVES To detect the prevalence and antibiotic susceptibility pattern of Pseudomonas aeruginosa isolates from wound infections. Materials and Methods A total of 100 samples were collected from both male and female patients of all ages of both IP and OP patients attending Saveetha Medical college and hospital Thandalam Chennai. Swabs were taken from wounds by the use of swab sticks and scalpel blades. The antibiotic disc used were Amikacin, Gentamicin, Amoxycillin, Tetracycline, Ampicillin and Ofloxacin. The results were interpreted as sensitive or resistant based on CLSI guidelines. RESULTS In our study on antibiotic susceptibility pattern of P.aeruginosa isolates the percentage of resistant strains 51% and 35.5% respectively against gentamicin and amikacin. In our study the most number of strains were susceptible to ofloxacin(75.5%), gentamycin(58.5%), ceftriazone(56.3%) which could be used as reserve drugs in case of severe illiness due to pseudomonas infection. CONCLUSION The result of this research showed that Pseudomonas aeruginosa was the most frequent pathogen isolated accounting for the total no of cases seen in Saveetha medical college. The susceptibility profile of P.aeruginosa isolates to the ten antimicrobials tested in vitrowere relatively low compared to the sensitivity pattern to different antipseudomonal drugs reported worldwide.