Prevalence and Antimicrobial Resistance Pattern of Methicillin Resistant Staphylococcus aureus in a Tertiary care Hospital Kulasekhram, Kanyakumari

Dr.Greesh.K

Volume : VIII, Issue : V, May - 2019

Prevalence and Antimicrobial Resistance Pattern of Methicillin Resistant Staphylococcus aureus in a Tertiary care Hospital Kulasekhram, Kanyakumari

Dr. Greesh. K

Abstract :

Introduction : Staphylococcus aureus is responsible for causing a variety of human infections, which may range from minor skin disease to life threatening infections.It colonize the healthy individuals and cause severe infections in hospitalised patients.The emergence of methicillin resistance S.aureus (MRSA) has posed a serious therapeutic challenge.Aim of the present study was to determine the prevalence of MRSA and their sensitivity pattern in a tertiary care hospital between june 2014 to july 2015 . Materials and Methods : In this study total 100 staphylococcus aureus was isolated from various clinical samples .Antimicrobial sensitivity test done by Kirby Bauer disk diffusion method and screening of MRSA was done by cefoxitin (30) disc by disk diffusion method as per clinical and laboratory standards guidelines.Result:Among 100 S.aureus ,25 isolates were MRSA(25%)and the female were dominant (13 isolates) which was 52%.maximum number of MRSA isolated from above 60 age group (56%). Majority of MRSA isolated from pus samples (68%). All the MRSA isolates were resistant to penicillin. Resistance to erythromycin was 24 isolates (96%) followed by resistance to ciprofloxacin was (76%),resistance to gentamicin was (32%). All the MRSA isolates were sensitive to vancomicin and teicoplanin (100%), followed by chloramphenicol,clindamicin,novobiocin,netilmicin was (96%),sensitive to cotrimoxazole were (88%),followed by tetracycline , amikacin were( 80%).