Prevalence and etiology of neonatal thrombocytopenia in tertiary care NICU

Dr.Dipak Madavi; Dr.Shamama Subuhi

Volume : VIII, Issue : IX, September - 2019

Prevalence and etiology of neonatal thrombocytopenia in tertiary care NICU

Dr. Dipak Madavi, Dr. Shamama Subuhi

Abstract :

Context: Thrombocytopenia is one of the commonest haematological disorders in the neonatal period, affecting up to a third of those admitted to neonatal intensive care units. It is well recognized that many feto maternal and neonatal conditions are associated with thrombocytopenia like maternal eclampsia, Prematurity, Sepsis, Hypoxia, intrauterine growth retardation, and disseminated intra vascular coagulation play an important role in the etiology of neonatal thrombocytopenia. Methods & material: 140 Newborn admitted in tertiary care NICU were selected to find out prevalence and etiology of neonatal thrombocytopenia. Detail maternal history and neonatal physical examination done and Neonates were followed for outcome , relevant investigation done according to cases. Result: Out of 140 neonates 63 neonates had thrombocytopenia (45%). 42.8% neonates were premature out of which 63.3 % had thrombocytopenia. Other neonatal risk factor for thrombocytopenia are sepsis 38 (74.5%), SGA/IUGR 28(80%) and NEC 9(100%). Maternal risk factor for thrombocytopenia are eclampsia 81.8% and infection during pregnancy 72.72%. Conclusion:The prevalence of neonatal thrombocytopenia was 45% . The most common etiology associated with thrombocytopenia were maternal eclampsia, prematurity and sepsis. Followed by IUGR and NEC.