PREVALENCE OF ABNORMAL LIVER FUNCTION TEST IN TYPE II DIABETES MELLITUS IN IN URBAN SOUTH-INDIAN POPULATION

DR.T.RAMESH KUMAR; DR. A. REVATHI; Balan Uma maheswari

Volume : VII, Issue : III, March - 2018

PREVALENCE OF ABNORMAL LIVER FUNCTION TEST IN TYPE II DIABETES MELLITUS IN IN URBAN SOUTH-INDIAN POPULATION

Dr. T. Ramesh Kumar, Dr. A. Revathi, Balan Uma Maheswari

Abstract :

BACKGROUND

Abnormal liver function test results are more common in diabetes mellitus than in the non diabetic population as well as in patients with type 2 diabetes than in those with type 1 diabetes. The aim of this study was to determine prevalence of abnormal liver function test in patients with type 2 diabetes and to determine associated risk factors.

MATERIALS AND METHODS

The present study was a cross sectional study done on patients with diabetes of any duration, attending the diabetology OPD of Institute of social obstetrics and Kasturba Gandhi general hospital between January 2016 to June 2017. Total no of 160 patient were selected by convenient sampling method after satisfying the inclusion criteria. The selected patients underwent clinical and biochemical evaluations. The results were calculated using SPSS software and expressed in percentage.

RESULTS:

Of these 160 patients, Serum ALT and AST was found to be elevated in 43 patients(27%), Serum alkaline phosphatase was found to be elevated in 10 patients (6%), Serum bilirubin was found to be elevated in 4 patients (3%). There was no significant alteration in serum protein or albumin globulin ratio.

CONCLUSION

A high proportion of patients with diabetes mellitus have abnormal liver function tests that may be a marker for NASH and insulin resistance. Routine liver function screening is not being advocated in type 2 diabetics but emerging evidence suggests that abnormal LFT may be a marker for metabolic syndrome.