Prevalence of HBsAg among Psoriasis patients attending Dermatology Outpatient Department, Tertiary Care Centre at Karaikal.

Dr Sivakumar Sivasubramanian; Dr Kode Leela Sravanthi

Volume : IX, Issue : V, May - 2020

Prevalence of HBsAg among Psoriasis patients attending Dermatology Outpatient Department, Tertiary Care Centre at Karaikal.

Dr Sivakumar Sivasubramanian, Dr Kode Leela Sravanthi

Abstract :

Background: Psoriasis is a chronic inflammatory disease involving complex abnormalities of epithelial growth and differentiation related to biochemical and immune responses[1]. Based on recent studies, on evaluating the relationships between psoriasis and systemic diseases, such as cardiovascular disease and metabolic syndrome, psoriasis has been accepted as a systemic inflammatory disease[2]. Among infectious diseases, hepatitis B virus (HBV) is the cause of chronic liver disease. As both psoriasis and viral hepatitis share the common characteristics of chronic inflammation and immune response, it has been hypothesized that HBV may trigger or aggravate psoriasis. Methodology: We analyzed prevalence of HBV infection and psoriasis and the relationship between them from 100 patients who visited the Department of Dermatology at Vinayaka Missions Medical College , Karaikal from July 2019 to September 2019. Data were analyzed using SPSS version 13.0. P values ≤0.05 were considered significant number. Results: A total of 100 patients (57 men & 43 women) with psoriasis were evaluated for HBV infection. The 2 patients of 100 psoriasis patients were on diagnosis of HBV and other 7 patients of psoriasis group were positive of HBs Ag test. Therefore, HBV infection of psoriasis group was 9 patients. Conclusion: This study to investigate the epidemiologic association between psoriasis and HBV infection did not find a significant prevalence of HBV infection in patients with psoriasis. However, a larger population–based study may help to clarify the findings of this study.