Recovery characteristics of sevoflurane versus halothane in children aged 1-3 years -- A comparative study.

Kouser Benazir; Javid Ahmad Dar; Mudhabir Ashraf

Volume : IX, Issue : VI, June - 2020

Recovery characteristics of sevoflurane versus halothane in children aged 1-3 years -- A comparative study.

Kouser Benazir, Javid Ahmad Dar, Mudhabir Ashraf

Abstract :

Background: The main objective of this study was to compare the recovery characteristics of sevoflurane and halothane for day–care anaesthesia in children aged 1–3 yr. Methods: 40 children undergoing day–care surgery were randomly divided into 2 groups of 20 each to receive inhalational induction with either sevoflurane or halothane and nitrous oxide in oxygen (70/30) via a face mask. Tracheal intubation was performed without a muscle relaxant. Anaesthesia was continued with the volatile anaesthetic, adjusted to maintain heart rate and blood pressure within ±20% of initial values. Recovery was evaluated using a modified Aldrete score, a Pain/ Discomfort scale and by measuring recovery end–points. A postoperative questionnaire was used to determine the well–being of the child at home until 24 h after discharge. Results: Emergence and interaction occurred significantly earlier after sevoflurane than halothane but discharge times were similar. More children in the sevoflurane group achieved full Aldrete scores within the first 30 min after anaesthesia, although this group suffered more discomfort during the first 10 minutes. The amount of postoperative analgesic administered was higher and the first dose given earlier in the sevoflurane group. Postoperative vomiting was more common with halothane, but side–effects in the two groups were otherwise similar in the recovery room and at home. Conclusions: In children 1–3 yr, sevoflurane provided more rapid early recovery but not discharge after anaesthesia of < 30–min duration. Apart from more vomiting with halothane and more discomfort during the first 10 min after awakening with sevoflurane, the quality of recovery was similar with the two anaesthestics.