Role of NT-pro BNP and 2D-Echo to exclude heart failure in case of Acute Exacerbation of COPD (AECOPD)

Dr Himmat Singh Rathore; Dr Suresh Sharma; Dr Basanta Hazarika; Dr Jogesh Sarma

Volume : VIII, Issue : V, May - 2019

Role of NT-pro BNP and 2D-Echo to exclude heart failure in case of Acute Exacerbation of COPD (AECOPD)

Dr Himmat Singh Rathore, Dr Suresh Sharma, Dr Basanta Hazarika, Dr Jogesh Sarma

Abstract :

Co–existing heart failure and AE–COPD may present as a diagnostic challenge, because of the frequent overlap amongst their signs and symptoms like exertional eathlessness, cough and paroxysmal nocturnal dyspnoea. The objective of the present study was to test the hypothesis that NT–pro–BNP and 2D–Echo can exclude heart failure in patients of AE–COPD. A prospective, hospital based single–centered study conducted in the department of Pulmonary Medicine at Gauhati Medical College & Hospital, Guwahati in a total of 96 patients hospitalized for AE–COPD. Clinical, biochemical data, serum NT–proBNP levels and 2D–Echocardiogram were recorded in all patients.2D–Echo was considered as gold standard for diagnosing heart failure. Cut–off level of NT–proBNP for diagnosing heart failure was taken> 500pg/ml and was compared with 2D–Echo.