Role of TRUS guided biopsy in prostatic lesions and its histopathological correlation

A K Mandal; Rakesh Mehra

Volume : VIII, Issue : VI, June - 2019

Role of TRUS guided biopsy in prostatic lesions and its histopathological correlation

A K Mandal, Rakesh Mehra

Abstract :

Background : Transrectal ultrasound–guided prostate biopsy (TRUS) has become essential in diagnostic investigation of prostatic lesions due to gland alterations resulting from abnormality on the digital rectal examination or rising of the prostatic specific antigen (PSA).It is considered as gold standard method to collect material for histopathological analysis Aim of the study: To evaluate the role of transrectal prostate ultrasound in the screening for prostate lesions and in the guidance of prostate biopsies. Materials and Methods: This study included 50 patients having symptoms suggestive of prostatic diseases. All these patients were subjected to DRE, serum prostate–specific antigen testing, transabdominal ultrasound examination and TRUS, as well as histopathological correlation Results: Among the 50 patients studied, final diagnosis by TRUS–guided biopsy revealed benign prostatic hyperplasia in 26 patients , which was the most common pathology, precancerous lesions in 1 patient , prostatitis in 4 patients, and prostatic adenocarcinoma in 19 patients (10%). All the cases were correlated with PSA levels and histopathology. Conclusion: TRUS guided biopsy in correlation with serum prostate–specific antigen levels and findings from DRE proves to be an effective modality in the diagnosis of prostatic lesions