Sarcopenia assessment by different methods (MRI-L3 SMI Index, Subjective Global Assessment and Handgrip Strength) as Predictive Factors in Patients with Liver Cirrhosis

Kandarp Nath Saxena; Rohan Mahajan; Amit Mathur; Ramesh Roop Rai; Shankar Lal Jat

Volume : VIII, Issue : IV, April - 2019

Sarcopenia assessment by different methods (MRI-L3 SMI Index, Subjective Global Assessment and Handgrip Strength) as Predictive Factors in Patients with Liver Cirrhosis

Kandarp Nath Saxena, Rohan Mahajan, Amit Mathur, Ramesh Roop Rai, Shankar Lal Jat

Abstract :

Introduction: Malnutrition is common in patients with chronic liver disease. We aimed to assess the value of malnutrition assessment tools (BMI, MAMC, SGA, HG and MRI L3–SMI Index) in predicting severity and survival of patients with liver cirrhosis Material and Methods: Eligible patients were cirrhotics of all etiology and severity who were admitted at department of gastroenterology, NIMS medical college, Jaipur between August 2016 and July 2018. Anthropometric evaluation was performed at the time of referral, according with the ISAK manual of International Society forthe Advancement of Kinanthropometry. Nutritional assessment was performed in all patients using SGA score on the day of admission. We measured the handgrip strength a hydraulic dynamometer Jamar® previously adjusted to the patient hand size was used. A transverse MRI image was taken from third lumbar vertea (L3) in department of radiology at NIMS Results: Patients were mainly men (81.7 %), with mean age of 44 ± 13.5 (Range 13–79 years). MAMC, HG and L3–SMI Index mean values were significantly lower with increasing cirrhosis severity as estimated by Child–Pugh class, MELD and MELD–Na scores. There is highest significant correlation between L3–SMI Index by MRI and severity of liver disease Conclusion: Our study show that nutritional parameter such as MAMC, HG, SGA and L3 –SMI Index by MRI are fair predictors of disease severity in cirrhotic patients