SCRUB TYPHUS: A PROSPECTIVE OBSERVATIONAL STUDY IN A TERTIARY CARE HOSPITAL DURING AN OUTBREAK IN EASTERN RAJASTHAN

DR ABDUL WAHID; DR ARUN VINAYAGAN; DR GIRISH CHANDRA VERMA; DR DHEERAJ SINGH SHEKHAWAT

Volume : VIII, Issue : XI, November - 2019

SCRUB TYPHUS: A PROSPECTIVE OBSERVATIONAL STUDY IN A TERTIARY CARE HOSPITAL DURING AN OUTBREAK IN EASTERN RAJASTHAN

Dr Abdul Wahid, Dr Arun Vinayagan, Dr Girish Chandra Verma, Dr Dheeraj Singh Shekhawat

Abstract :

Objective : To study the clinical profile, epidemiology, complications, and outcome of scrub typhus in eastern Rajasthan. Method: This prospective study was conducted in indoor patients of Government Medical College, Kota from August 2018 to November 2018. 50 cases of scrub typhus IgM was included in the study with the age group between 10 year and 80 years. Results: Among 50 patients, majority of the patients were females in the age group 30–50 yrs. Most common symptoms were fever, cough with shortness of eath, gastrointestinal symptoms, altered sensorium and bleeding manifestation. Eschar, bilateral pulmonary infiltrates, splenomegaly, and polyserositis were noticed. Some atypical manifestations like hypertriglyceridemia, T inversion V2, V3, reversible pancytopenia, acute cerebellitis and one patient with macroamylasemia with normal pancreas were noticed. Out of 50 patients 13 died due to the complications of septicemia, fulminant hepatic failure, ARDS, encephalitis, sub arachnoid haemorrhage and perforation peritonitis. Rest of them respond to treatment with Doxycycline and azithromycin and recovered well without any residual impairement. Conclusion : Eastern Rajasthan witnessed an outeak of scrub typhus. High index of suspicion based on clinical features with or without eschar and prompt therapy with specific antibiotic will result in complete recovery from scrub typhus and favourable outcome.