Volume : VII, Issue : V, May - 2018

SERUM MMP-7 LEVELS AS A PREDICTOR OF KNEE OSTEOARTHRITIS SEVERITY

Blondina Marpaung, Ok Moehad Sjah

Abstract :

This objective of this study was to evaluate the accuracy of MMP–7 in predicting severe degree of osteoarthritis (OA).A cross–sectional study was done on 55 consecutive knee OA patients that were admitted to Rheumatology division at Adam Malik General Hospital Medan, Indonesia.Disease severity in the knee OA patients was assessed using the Kellgren–Lawrence (K–L) grading scale.Serum MMP–7 levels were examined in serum using the Quantikine Human MMP–7–ELISA. Serum MMP–7 levels were significantly higher in moderate + severe knee OA than mild knee OA patients. MMP–7 was able to predict the severity of OA. Levels of MMP–7> 12.65 pg/mL were able to predict moderate + severe OA with 66.7% sensitivity and 68.2% specificity.

Article: Download PDF    DOI : https://www.doi.org/10.36106/paripex  

Cite This Article:

Blondina Marpaung, OK Moehad Sjah, SERUM MMP-7 LEVELS AS A PREDICTOR OF KNEE OSTEOARTHRITIS SEVERITY, PARIPEX‾INDIAN JOURNAL OF RESEARCH : Volume-7 | Issue-5 | May-2018

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