SPECTRUM OF INDICATIONS AND FINDINGS OF BONE MARROW EXAMINATION IN NEONATES AT A TERTIARY CARE CENTER FROM INDIA

Dr. Krishna Chaitanya

Volume : VIII, Issue : II, February - 2019

SPECTRUM OF INDICATIONS AND FINDINGS OF BONE MARROW EXAMINATION IN NEONATES AT A TERTIARY CARE CENTER FROM INDIA

Dr. Krishna Chaitanya

Abstract :

OBJECTIVES: Bone marrow examination is one of the most valuable procedures in the evaluation of haematological disorders. There is a shortage of published literature regarding the indications, procedure, and outcome of BME in neonates. The aim of the present study is to analyse the common indications of performing BME, to assess the findings and spectrum of disorders diagnosed by it in neonates. METHODS: A retrospective analysis of BMEs performed in neonates over a period of 24 months, between 2015 and 2017 was done. RESULTS AND DISCUSSION: A total of 12 BME were performed on 12 neonates, which constitutes 10.3% of pediatric BME procedures during the same period. In our institute, BME is routinely performed by trained haemato–oncologist from posterior superior iliac spine in neonates with an overall sample adequacy of 97%. Evaluation of cytopenias was the most common indication for BME procedure, while normal marrow and myeloid hypoplasia due to sepsis were the most common diagnoses offered in neonatal BM. CONCLUSIONS: Posterior superior iliac spine is a good site of BME in neonates in trained hands. BME not only helps to make specific diagnoses but should also be used as an extremely valuable and economically viable procedure to exclude major haematological disorders and malignancies in this age group