SPECTRUM OF MAGNETIC RESONANCE IMAGING IN EVALUATION OF CENTRAL NERVOUS SYSTEM LESIONS IN HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENTS

Dr. Abhishree Geda; Dr. Alka Agrawal; Dr. Devashish Mishra

Volume : VII, Issue : III, March - 2018

SPECTRUM OF MAGNETIC RESONANCE IMAGING IN EVALUATION OF CENTRAL NERVOUS SYSTEM LESIONS IN HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENTS

Dr. Abhishree Geda, Dr. Alka Agrawal, Dr. Devashish Mishra

Abstract :

The present study was undertaken to determine the role of MRI and Diffusion weighted imaging along with contrast and MRS in the identification and characterization of CNS lesions in HIV positive patients. The purpose of study was to characterize and differentiate various CNS lesions on MRI in HIV positive patients. The study group comprised of 62 patients with neurological involvement due to HIV or associated opportunistic infections and other HIV associated pathologies. In our study 69.4% cases of opportunistic infections, 11.29% cases of neoplastic and 19.35% cases of lesions due to HIV and immune system per se were found. Tuberculosis was the most common opportunistic infection 46.8% diagnosed by MRI, followed by toxoplasma 8.1%. It is recommended that in all HIV positive patients MRI should be combined with DWI, contrast and MRS which plays a crucial role in the diagnostic evaluation of patients suffering from CNS manifestations of HIV infection.