Statin induced de-novo late onset myasthenia gravis after coronary bypass surgery

Himanshu Arora; Arun Mohanty; Samhita Panda; Sandeep Parekh

Volume : VII, Issue : VII, July - 2018

Statin induced de-novo late onset myasthenia gravis after coronary bypass surgery

Himanshu Arora, Arun Mohanty, Samhita Panda, Sandeep Parekh

Abstract :

Drug induced myasthenia gravis is a rare clinical presentation of late onset myasthenia gravis. We report a case of a 58–year–old gentleman who was prescribed high dose rosuvastatin after undergoing coronary artery bypass graft for acute coronary syndrome. He developed fluctuating oculobulbar weakness within one month of initiation of statin and was diagnosed as having myasthenia gravis. Remission was achieved after rosuvastatin was stopped along with immunomodulation. This case highlights that use of statins can induce or aggravate myasthenia gravis in susceptible patients.