Structural, Free Radical Scavenging activity and ?- glucosidase inhibition of Newly Synthesized complexes of copper(II) with L-Cystein, Methionine and Threonine

Prof. I. P. Tripathi; Dr Aarti Kamal

Volume : VII, Issue : IV, April - 2018

Structural, Free Radical Scavenging activity and ?- glucosidase inhibition of Newly Synthesized complexes of copper(II) with L-Cystein, Methionine and Threonine

Prof. I. P. Tripathi, Dr Aarti Kamal

Abstract :

A new series of closely related yet distinct dinuclearCu(II) complexes, obtained upon subsequent complexation with all these ligands, are investigated for their structural properties and for their ability to exhibited effective α–glucosidase inhibition. These activity studies are mainly focused on evaluating antioxidant activity. The complex of L–theonine effective on the proton release in DPPH assay with an IC₅₀ value of 92.17μM and also exhibited the highest activity in ABTS scavenging with an IC₅₀ of about 61.07 μM for L–cysteine amongst the synthesizedmetal complexes. A perusal of the data reveals that these complexes of Cu(II) with L–methionine shows effective alpha–glucosidase activity exhibits.