PARIPEX - Indian Journal of Research

Dr. Poulomi Saha; Dr. Kapildev Mondal

Volume : IX, Issue : II, February - 2020

Study of Allergic rhinitis and its impact on PFT in pre-teen and Teen age group

Dr. Poulomi Saha, Dr. Kapildev Mondal

Abstract :

BACKGROUND: Because of this shared pathophysiology, World Health Organization has promoted the idea of ‘one airway, one disease’ —i.e., that allergic rhinitis and asthma are different manifestations of the same disease. Significant onchial obstruction may be present in asymptomatic asthmatic adolescents and young adults. We aimed to assess the diagnostic value of two major PFTs individually and measure serum IgE to identify the patients with poor lung function with potential risk of asthma in known cases of allergic rhinitis in pre–teen(11 years and 12 years) and teen(13–19 years) age. METHOD: Three thousand one hundred and five (3105) patients (age group 10 – 19 years) attending the out–patient department for AR were evaluated. They were further subdivided in 3 groups depending the duration of symtoms(0–12 months,12–24 months and 24–36 months . According to GINA guideline the patients were subjected to spirometry to measure FEV1/FVC ( ratio of forced expiratory volume in 1 s [FEV1] to forced vital capacity [FVC] <0.7) and onchodilator reversibility( ≥12% ).Then serum IgE was measured. We considered serum IgE levels of 100 IU/mL as cutoff. RESULT: In our study 63.2% patients had shown FEV1/FVC less than 0.7 and out of that 59.3%%patients had shown onchodilator reversibility. 84.3% patients had elevated lavel of sIgE. In pre–teen age group(11–12 years) out of 882 patients,514(16.5%) patients had FEV1/FVC below 0.7 out of which 482 (15.5%)patients had shown onchodilator reversibility. In teen aged patients, 13–15 years and 16–19 years, FEV1/FVC less than 0.7, were noted subsequenty in 817(26.3%) and 635(20.4%) patients. 776(24.9%) patients of 13–15 years out of 817 and 588(18.9%) patients of 16–19 years out of 635 patients have shown onchodilator reversibility. CONCLUSION: Our findings of FEV1/FVC, onchodilator reversibility and serum IgE measurement show good approximation of the changes in in lung function observed over time and adequately describepulmonary function in growing subjects Pulmonary function tests (PFTs) are useful for diagnosing the cause of unexplained respiratory symptoms and monitoring patients with known respiratory hyperactive airway disease.