STUDY OF CASES OF ERYTHROID HYPERPLASIA IN BONE MARROW EXAMINATION AND THEIR CORRELATION WITH VITAMIN B12, FOLIC ACID AND IRON LEVELS, IN RIMS, RANCHI

Dr. Satyajeet; Dr. Ajay Kumar Shrivastava

Volume : VIII, Issue : VI, June - 2019

STUDY OF CASES OF ERYTHROID HYPERPLASIA IN BONE MARROW EXAMINATION AND THEIR CORRELATION WITH VITAMIN B12, FOLIC ACID AND IRON LEVELS, IN RIMS, RANCHI

Dr. Satyajeet, Dr. Ajay Kumar Shrivastava

Abstract :

INTRODUCTION: Nutritional anemia is very prevalent in India, especially in rural parts of Jharkhand. These nutritional anemias can be pretty accurately diagnosed using biochemical tests, still these are largely being diagnosed on bone marrow aspirations, which is an invasive process having its own risks. OBJECTIVE: To study the cases of erythroid hyperplasia in bone marrow examination and its correlation with levels of iron(ferritin), vitamin B12 and folic acids. MATERIALS & METHODS: 100 cases of erythroid hyperplasia were taken and 100 controls without erythroid hyperplasia.Their serum levels of ferritin, vitamin B12 and folic acid were taken. A correlation was then made between occurrence of erythroid hyperplasia and nutritional deficiencies of iron, vitamin B12 and folic acid. RESULTS: Cases had significantly higher incidence of nutritional deficiencies as compared to controls. CONCLUSION: Nutritional anemias of iron, vitamin B12 and folic acid deficiencies, which are very common in India, can be pretty accurately diagnosed by biochemical tests. Bone marrow aspiration should be reserved for atypical presentations