Study of changes in Lipid profile in patients with Hypothyroidism belonging to tribal population of Northern Maharashtra

Sandip Lambe; Pankaj Kambale; Kanchan Lambe; Kalpana Rakshit

Volume : VIII, Issue : V, May - 2019

Study of changes in Lipid profile in patients with Hypothyroidism belonging to tribal population of Northern Maharashtra

Sandip Lambe, Pankaj Kambale, Kanchan Lambe, Kalpana Rakshit

Abstract :

The cross sectional study of changes in lipid profile in patients with Hypothyroidism was conducted in a tertiary care of hospital in northern Maharashtra region with the sole purpose of compare and correlate the changes in the levels of lipid profile occurring in hypothyroidism patients. There is a profound effect of thyroid hormones on lipid profile. Serum levels of total cholesterol, triglycerides, HDL, LDL and VLDL cholesterol were estimated in 100 newly diagnosed hypothyroidism patients and 100 normal healthy controls enrolled in the study. The results obtained in our study indicated raised serum total cholesterol, triglycerides, LDL and VLDL cholesterol levels and decreased serum HDL cholesterol levels. In addition increase in levels of serum total cholesterol, triglycerides, LDL and VLDL cholesterol correlated positively with serum TSH levels in hypothyroidism patients while decrease in the levels of serum HDL cholesterol correlated negatively with serum TSH levels in hypothyroidism patients. Hence the present study mandates the estimation of lipid profile in all hypothyroidism patients to prevent the development of cardiovascular events