STUDY OF HISTO-MORPHOLOGICAL SPECTRUM OF TUBULO-INTERSTITIAL DISEASES OF KIDNEY IN A TERTIARY CARE HOSPITAL

Anita A M; Md Hamed Altaf Mali; Anuradha G Patil

Volume : VIII, Issue : V, May - 2019

STUDY OF HISTO-MORPHOLOGICAL SPECTRUM OF TUBULO-INTERSTITIAL DISEASES OF KIDNEY IN A TERTIARY CARE HOSPITAL

Anita A M, Md Hamed Altaf Mali, Anuradha G Patil

Abstract :

AIM : To study the various patterns of Tubulo–interstitial diseases of kidney with their clinic– pathological correlation in a tertiary care hospital in North–Karnataka region. MATERIALS AND METHODS : This study was conducted over a period of eighteen months from JuLY 2017 – December 2018 after approval from the Institutional Ethical Committee . A total of 100 renal samples were studied . Inadequate and samples from the renal transplant patients were excluded from the study . RESULTS : Out of total hundred renal lesions, twenty one cases were of tubulo –interstitial diseases of kidney . Out of these, thirteen cases were of Acute Tubular Injury , five cases of Acute interstitial nephritis and three cases of chronic interstitial nephritis . Also, in this study, four cases of secondary acute tubular injury were associated with each case of IgA nephropathy, minimal change nephropathy focal segmental glomerulosclerosis and arterio–nephrosclerosis respectively. Diabetic nephropathy was associated with two cases of interstitial nephritis. Most common clinical presentations were deranged renal functions and raised serum creatinine. Conclusion : This study was undertaken to study histo–morphological patterns, clinical correlation and etiopathogenesis of various Tubulo–interstial diseases of kidney.