Study of microbial agents and their sensitivity pattern to 1st and 2nd line of antibiotics in patient with urinary tract infection.

Dr. Abhishek Kumar; Dr Ruchi Singh

Volume : VII, Issue : I, January - 2018

Study of microbial agents and their sensitivity pattern to 1st and 2nd line of antibiotics in patient with urinary tract infection.

Dr. Abhishek Kumar, Dr Ruchi Singh

Abstract :

AIM

1. To Study the Microbial Agents including Bacteria & Yeasts Responsible for UTI in Patient attending both OPD and IPD at Index Medical College Hospital & Research Centre, Indore.

2. To Study the Antimicrobial Sensitivity Patterns of bacterial Uropathogens.

MATERIAL AND METHODS: Urine samples were collected from patients attending the OPD and IPD. 300 Mid stream urine samples from patient showing presumptive symptoms of UTI were collected taking all aseptic precautions. Urine Analysis,Wet mount preparation, gram staining, isolation on Cled agar, Blood agar, Leukocyte esterase AST done by Kirby Bauer method and ESBL detection by double disk method and biochemical reaction was done.

RESULTS: E.coli was the most common uropathogen isolated.Anti microbial susceptibility pattern of E.Coli showed maximum sensitivity to Amikacin 69% and Nafcillin (50%) and maximum resistance was seen with Nitrofuratoin (68%) Peniciline G (67%) .

CONCLUSION: E.coli was the most common cause of UTI in community and hospital and amikacin is an effective drug against it.