STUDY OF PROGNOSTIC MARKERS OF AMOEBIC LIVER ABSCESS IN REFERENCE TO ALCOHOLIC AND NON-ALCOHOLIC CASES

Dr. Prabhat Ranjan; Dr. Akhilesh Kumar; Dr. Saurabh Kumar

Volume : VIII, Issue : II, February - 2019

STUDY OF PROGNOSTIC MARKERS OF AMOEBIC LIVER ABSCESS IN REFERENCE TO ALCOHOLIC AND NON-ALCOHOLIC CASES

Dr. Prabhat Ranjan, Dr. Akhilesh Kumar, Dr. Saurabh Kumar

Abstract :

BACKGROUND : Amoebic Liver Abscess is common parasitic disease in developing countries and alcohol is important risk factor for Amoebic Liver Abscess. Poor prognosis is more commonly seen in alcoholics+/–HIV individuals than non alcoholics. Hence prognostic markers are identified, so that aggressive treatment can be instituted. AIM: To determine the good and poor prognostic markers in non alcoholic and alcoholics cases and comparison between them. Methods: Prospective study of 60 cases of amoebic liver abscess was done. Prognostic markers were identified by clinical, biochemical, ultrasonography and aspiration of content. Patients were followed up till clinical resolution of symptoms. RESULTS: A stepwise logistic regression suggested that S. Bilirubin > 3.5 mg/dl, Serum Albumin < 2 g/dl, volume of abscess > 500/ml, multiple abscess are independent risk factor for morbidity and mortality. Bad prognosis (two cases) were encountered in study. CONCLUSION: poor prognostic markers were more common among alcoholic cases. Hence, identification with poor prognostic factor is of clinical relevance.