STUDY OF SERUM MAGNESIUM LEVEL IN TYPE 2 DIABETES MELLITUS PATIENTS AND ITS RELATION WITH GLYCEMIC CONTROL OF PATIENTS.

Praveen Kumar Baghel; Nitin Pandey; Sneh Jain

Volume : VIII, Issue : X, October - 2019

STUDY OF SERUM MAGNESIUM LEVEL IN TYPE 2 DIABETES MELLITUS PATIENTS AND ITS RELATION WITH GLYCEMIC CONTROL OF PATIENTS.

Praveen Kumar Baghel, Nitin Pandey, Sneh Jain

Abstract :

INTRODUCTION: Diabetes is an iceberg disease, the prevalence of diabetes in adults was around 4% worldwide.The recent WHO report suggests that over 19% of worlds diabetic population currently resides in India.Patient with longer duration of diabetes had higher mean HbA1c values and lower mean magnesium values. Hypomagnesemia may lead to the induction of pro inflammatory and profiogenic response, cause in–duction or augmentation of vasoconstriction and hypertension.Patient with longer du–ration of diabetes had higher mean HbA1c values and lower mean magnesium values. OBJECTIVE:To study the distribution of serum magnesium level in relation to HbA1c level, FBS, duration of diabetes and demographic profile of patients. MA–TERIALS AND METHODS: This cross sectional analytical study was carried out in our institution for duration of 1 year.Total of 500 subjects were enrolled in the study.Detailed clinical and demographic profile including duration of diabetes and patients were investigated for HbA1c level,FBS.The data were analysed using SPSS Version 16.RESULT: Prevalence of hypomagnesemia in type 2 diabetes was 33% with serum magnesium level 1.31± 0.087 mg/dl. Hypomagnesemia has significant as–sociation with glycemic control which was reflected in uncontrolled fasting blood sugar (FBS >126 mg%) (p value 0.001) and HbA1c >7% (p value 0.0001).It has sig–nificant reverse correlation with duration of diabetes(p value = 0.0004) CONCLU–SION:Our study showed significant correlation between hypomagnesimia and uncon–trolled glycemic status and duration of diabetes that will indicate magnesium plays an important role in glucose metabolism