Study of Serum Prostate specific antigen and Age specific distribution in Benign enlargement of prostate and carcinoma of prostate.

Dhananjay Bhale; Ruta Anandgaonkar; D.M. Vaishnav

Volume : VII, Issue : VIII, August - 2018

Study of Serum Prostate specific antigen and Age specific distribution in Benign enlargement of prostate and carcinoma of prostate.

Dhananjay Bhale, Ruta Anandgaonkar, D. M. Vaishnav

Abstract :

INTRODUCTION:Benign prostatic hyperplasia is the most common neoplastic disorder affecting the aging male population worldwide. AIMS AND OBJECTIVES:To study Serum PSA levels in patients of benign enlargement of prostate and cancer of prostate . MATERIAL AND METHODS: The present study was carried out in Department of Biochemistry in collaboration with Central Laboratory and Department of Urology, MGM Medical College, Aurangabad from November 2015 to November 2017. Serum PSA levels were measured on VITROUS 5600 by Enhanced Chemiluminescence method. In the present study, the mean PSA in Group B was 19.21±11.95 ng/ml which was comparatively higher than Group A. This mean difference of PSA between two groups was found to be statistically significant ( p<0.0001). The mean age of Group A was 66.02±10.05 years whereas in Group B the mean age was 68.38± 8.49 years. SUMMARY AND CONCLUSION:In this study, higher serum PSA levels were observed in the benign and malignant group both suggesting a potential correlation between prostate inflammation and prostate cancer.