Study of uropathogens and antibiotic susceptibility in cases of urinary tract infections (UTI) in Rama Medical College and Hospital, Hapur.

Dr. Muzaffari Yasmeen; Dr. Md Rashid Taj

Volume : VIII, Issue : XI, November - 2019

Study of uropathogens and antibiotic susceptibility in cases of urinary tract infections (UTI) in Rama Medical College and Hospital, Hapur.

Dr. Muzaffari Yasmeen, Dr. Md Rashid Taj

Abstract :

Background: One of the most common infectious diseases diagnosed in developing countries is urinary tract infection (UTI). extensive exercise of antibiotics in opposition to uropathogens has led to the appearance of antibiotic resistant. A laboratory based cross–sectional survey was conducted in Rama Medical College and Hospital to determine the prevalence and antibiotic susceptibility of uropathogens in hapur district . Methods: We have collected 101 clean catch mid–stream urine samples from all suspected UTI using sterile screw capped container. The urine samples were cultured and processed for subsequent uropathogens isolation. The identified species were then exposed to selected antibiotics to test for their susceptibility. Results: The overall prevalence of urinary tract infection in the area was 60.39%. Most frequently isolated uropathogen in our study was Escherichia coli was the most prevalent bacterial uropathogen with 21/61 (34.5%) followed by Staphylococcus aureus 16/61 (26.2%), Klebsiella pneumoniae 12/61 (19.6%), Proteus mirabilis 1/61 (1.2%), Enterococcus faecalis 6/61(9.8%), and Proteus aeruginosa 2/61 (3.2%). Escherichia coli was mostly sensitive to Meropenam and Cefuroxime 17/21 (80.96%), Staphylococcus aureus highest sensitivity to piperacillin/tazobactam 14/16 (87.5%) . Sensitivity of Klebsiella pneumonia was good with most of the anti biotics with best result of gatifloxacin 11/12 (91.67%). Enterococcus faecalis was sensitive to almost all the antibiotics having 100% sensitivity to antibiotics like vancomycin, meropenam and piperacillin/tazobactam. Conclusion: The option of empirical antimicrobial treatment is notably affected by uropathogen prevalences according to age and gender . judicious use of antibiotic is important