SURGICAL MANAGEMENT OF SQUAMOUS CELL CARCINOMA OF MAXILLARY SINUS: A RETROSPECTIVE STUDY

TRIPATHI UMANK; KUMAR SHARATH K L; BANSAL VISHAL

Volume : VII, Issue : I, January - 2018

SURGICAL MANAGEMENT OF SQUAMOUS CELL CARCINOMA OF MAXILLARY SINUS: A RETROSPECTIVE STUDY

Tripathi Umank, Kumar Sharath K L, Bansal Vishal

Abstract :

Squamous cell carcinoma of maxillary sinus is a rare cancer among head and neck cancer whose optimal treatment is not well established and the outcome remains poor. AIMS: The purpose of this paper is to present the experience in the surgical management of patients with squamous cell carcinoma of the maxillary sinus. MATERIALS AND METHODS: A total number of 40 patients with squamous cell carcinoma of maxillary sinus were operated at our institute from August 2011 to August 2014. All patients underwent surgical excision of tumor, 26 patients (65%) were treated with surgery followed by postoperative radiotherapy. Surgery consisted of 27 total maxillectomy, 12 partial maxillectomy with preservation of orbital floor, one radical maxillectomy with orbital exenteration. Overall survival and disease free survival were calculated using the Kaplan–Meier method. RESULTS: Most(75%) patients presented in advanced stage. The 3 and 5–year overall survival of the 40 patients was 65% and 45% respectively. The 3 and 5–year disease free survival was 62.5% and 40% respectively. overall recurrence was seen in 21(52.5%) patients. The most common site of recurrence was in the primary site, which was observed in 17 of 40 patients (42.5%).CONCLUSION: Maxillary sinus squamous cell carcinoma is an aggressive tumor normally diagnosed at the advanced stage and most patients present an unfavorable prognosis and reduced survival rate. The addition of systemic therapy(Neoadjuvant and in adjuvant settings) to radiotherapy may improve overall survival in advanced squamous cell carcinomas of maxillary sinuses, which has to be evaluated in larger prsospective studies .