The Antibiotic susceptibility profile of Enterococcal isolates at a tertiary care Hospital.

Dr. Shreya Chaudhuri; Dr. M.S Qazi

Volume : VII, Issue : VI, June - 2018

The Antibiotic susceptibility profile of Enterococcal isolates at a tertiary care Hospital.

Dr. Shreya Chaudhuri, Dr. M. S Qazi

Abstract :

Objectives: The objective of the study was to determine the Antibiotic susceptibility profile of the Enterococcus species isolated from various clinical samples in a tertiary care hospital.

Material and Methods: Enterococcus species isolated from various clinical specimens were identified by the Conventional identification scheme by Faclam and Collins and their susceptibility to various antibiotics were detected by disc diffusion method and vancomycin susceptibility was further confirmed by determining MIC with E–strips.

Results:In this study,180 Enterococcal isolates were obtained from various clinical samples, from October 2014 to November 2016. Most common isolate wasEnterococcus faecalis (57.2%), followed by E. faecium(42.3%) and one isolate of E. hirae (0.5%). Resistance to penicillin was 90.56%. Although vancomycin resistance was low (1.67%) but resistance to high level gentamicin (81.11%) and high level streptomycin (72.22%) is a cause of great concern. None of the isolates were resistant to Linezolid.

Conclusion: The emergence of antibiotic resistance among enterococci, even to drugs like vancomycin is a cause of great concern. Linezolid appears to remain a last resort therapeutic option for enterococcal infections. Hence, the need of hour is to comply with judicious use of antibiotics.