The Differences Of Zinc And Albumin Levels Between Spontaneous Abortion And Normal Pregnancy

Murdayah; Yusrawati; Detty Iryani

Volume : VII, Issue : VIII, August - 2018

The Differences Of Zinc And Albumin Levels Between Spontaneous Abortion And Normal Pregnancy

Murdayah, Yusrawati, Detty Iryani

Abstract :

Background: Zinc is one of the elements essential mineral that is essential for cell growth, development and cell differentiation. This mineral circulates in the blood is bound by albumin around 70%, Zink and albumin have a role in the activity of the enzyme superoxide dismutase (SOD) as the body‘s defense system mainly from the activity of compounds of Reactive Oxygen Species (ROS), which can make oxidative stress and cause spontaneous abortion.This study aims to determine the levels of zinc and albumin difference between spontaneous abortion and normal pregnancy.

MethodThis study was an observational with cross sectional design study was conducted from July 24 until 24 September 2017 in dr. Rasidin Padang, RS TK III dr. Reksodiwiryo Health Center Andalas Padang and Padang. Serum examination in Biomedical Laboratory Padang Andalas University School of Medicine and Health Laboratory UPTD West Sumatra Province. Samples were taken from pregnant women diagnosed with spontaneous abortion and normal pregnant women with gestational age <20 weeks by 40 samples. Sampling consecutive sampling. The level of zinc and albumin through the blood serum examined by colorimetric method. Test data normality using Shapiro Wilk test followed by an unpaired t test.

result: The mean levels of zinc in spontaneous abortion group (105.99 ± 7.15) was lower than the normal pregnancy group (111.00 ± 9.06) with p = 0.06 and the mean levels of albumin in spontaneous abortion group (4, 29 ± 0.47) was lower than the normal pregnancy group (4.40 ± 0.33), with p = 0.407.

Conclusion: There is no significant difference between the levels of zinc and albumin spontaneous abortion and normal pregnancy.