The structural and functional relationship between changes in blood microcirculation and the ultrastructure of capillaries in muscles in response to physical training

Natalya H. Sydoriak; Vladimir P. Vyunitsky; Ekateryna R. Timoshenko; Maria V. Belikova; Ekateryna V. Rozova

Volume : VII, Issue : IV, April - 2018

The structural and functional relationship between changes in blood microcirculation and the ultrastructure of capillaries in muscles in response to physical training

Natalya H. Sydoriak, Vladimir P. Vyunitsky, Ekateryna R. Timoshenko, Maria V. Belikova, Ekateryna V. Rozova

Abstract :

The relationship between changes in blood microcirculation (BM) and the ultrastructure of muscles capillaries in response to the dosed physical training (DPT) in young people of varying degrees of fitness and animals under experimental conditions was studied. It was found that lack of fitness and/or initially low microcirculation index (BMI) are accompanied by a decrease in the effectiveness of blood flow regulation in response to DPT, while initially high values of BMI in sportsman indicate the possibility of compensatory increase in blood flow efficiency in the microcirculation system at DPT due to predominance of active regulatory mechanisms. In the experiment with DPT were revealed the ultrastructural manifestations of muscle adaptation, including initial signs of primary angiogenesis, the activation of mitochondrial morphogenesis. The formation of such compensatory and adaptive changes aimed at providing adequate energy metabolism and preventing the development of secondary tissue hypoxia. Along with this, in the muscular tissue (especially with DPT in untrained animals) there was a site of hypertrophy of muscles, and sometimes an increase in the percentage of structurally damaged organelles. Such multidirectional changes may indicate the individual peculiarities in the formation of adaptive mechanisms in the organism in response to the DPT and explain the variability of changes in the microcirculation system.