Thyroid profile in children on sodium valproate monotherapy

L A. Ravi; A. Viveka Saravanan; Namitha Rajendran; C. Leema Pauline

Volume : VII, Issue : IX, September - 2018

Thyroid profile in children on sodium valproate monotherapy

L A. Ravi, A. Viveka Saravanan, Namitha Rajendran, C. Leema Pauline

Abstract :

Objectives:. To study the thyroid profile in children on anticonvulsant sodium valproate monotherapy.Design: Cross sectional study. Setting: Tertiary care teaching hospital. Method:This study was done in 60 children with seizure disorder on sodium valproate monotherapy recruited between Jan 2017 to June 2017 at Institute of Child Health, Chennai. Demographic data including age, sex, type of epilepsy, duration of treatment were recorded and 2ml blood was collected for testing thyroid profile. Results: Majority belonged to 1–5 years age group. Males (63%) predominated the study. Generalised seizures were the commonest seizure type. 35% had high TSH values and 6.6% had lower thyroid hormone levels. None had clinical symptoms or signs of hypothyroidism.