TO STUDY EARLY NEURO-RETINAL DEGENERATION IN TYPE 2 DIABETES & COMPARE IT WITH NORMAL SUBJECTS WITH SPECTRAL DOMAIN OCT

Dr Anindita Das

Volume : IX, Issue : III, March - 2020

TO STUDY EARLY NEURO-RETINAL DEGENERATION IN TYPE 2 DIABETES & COMPARE IT WITH NORMAL SUBJECTS WITH SPECTRAL DOMAIN OCT

Dr Anindita Das

Abstract :

Aim: The aim of the following study is to evaluate the Central macular thickness (CMT), retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thickness in patients with type 2 diabetes mellitus (DM) and compare it with normal subjects of same age groups.. Materials and Methods: Central macular thickness (CMT), Retinal nerve fie layer ( RNFL) and Ganglion cell complex ( GCC) thickness were measured in 180 eyes using spectral domain optical coherence tomography. The values of participants with DM were compared to controls. Diabetic patients were collected in Groups 1, 2 and 3. Group 1 = 50 eyes who had no diabetic retinopathy (DR); Group 2 = 50 eyes who had mild nonproliferative DR and Group 3 = 40 eyes who had moderate non–proliferative DR. The 40 healthy( non–diabetic ) eyes collected in Group 4. Analysis of variance test used for statistical analysis. Results: The values of CMT, RNFL and GCC in the type 2 diabetes were thinner than controls and this difference was statistically significant. Conclusions: This study showed that there is a significant loss of CMT, RNFL and GCC in patients with type 2 diabetes.