Tobacco related oral lesions - Cyto-histological correlation in a tertiary care hospital of Odisha.

Dr. Gitimadhuri Dutta; Dr. Sujata Pujari; Dr. Asaranti Kar

Volume : VII, Issue : IV, April - 2018

Tobacco related oral lesions - Cyto-histological correlation in a tertiary care hospital of Odisha.

Dr. Gitimadhuri Dutta, Dr. Sujata Pujari, Dr. Asaranti Kar

Abstract :

Background:

Oral cancer is the commonest malignancy in Indian males. The incidence of oral squamous cell carcinoma appears to be directly related to use of tobacco in various forms.Tobacco related oral lesions havevaried presentations like erosive and ulcerative lesions, leukoplakia, proliferative verrucous carcinoma and squamous cell carcinoma.

Aims and objectives:

The present study aims to find the correlation between cytological (scrape) analysis and histopathological study in patients with tobacco addiction presenting with oral lesions.

Materials & methods:

The study was conducted in S.C.B.Medical College, Cuttack during the period from September, 2012 to August 2016.All the patients were subjected to clinical examination,scrape cytological assessment and histopathological study. The scrape smears were stained with Pap and H&E stain.

Results:Total number of patients in this study was 528 with M:F ratioof 1.65:1. Out of them,130 caseswere correlated with histopathological diagnosis. Maximum number of patients were addicted to Gutka (32.57%) . Majority of patients were in fifth and sixth decades of life(%). Squamous cell carcinoma (SCC) was predominantly seen in 6^th decade(%).Alvelolo–buccal complex is the commonest site of SCC of oral cavity. Sensitivity of our study was 97.27%, specificity 95% and positive predictive value(PPV)was 99%.

Conclusion: Scrape cytology is an easy ,rapid, economical and fairly accurate procedure to screen oral lesions. Early diagnosis ,increased awareness will result in effective,early treatment and prevention of complications with downstaging of oral cancers.