Volume : IV, Issue : V, May - 2014

10 Ghz Microwaves Induced Biochemical, Learning and Memory Alterations in Swiss Albino Mice Brain

Archana Sharma, Deepak Bhatnagar, Rashmi Sisodia

Abstract :

 The present study is an attempt to study the effects of 10 GHz (Giga Hertz) microwaves irradiation in Swiss 

albino mice. The animals of 6–8 weeks of age were divided into 2 groups – (i) sham exposed (ii) microwaves. 
The mice were exposed to 10 GHz microwaves daily for 2 hours per day for 30 days. The power density was 0.25 mW/cm2 
(milliwatt per centimeter square). Average whole body specific absorption rate (SAR) was calculated 0.1790 W/kg. After the 
exposure period the animals were sacrificed at different autopsy intervals viz., 1–30 days and the ain was excised to study 
various biochemical parameters. The animals were also tested in a radial arm maze to assess the learning and memory performance. Chronic exposure of these electromagnetic field radiations resulted in significant decrease in antioxidant enzyme 
activity of SOD (superoxide dismutase) and GSH (glutathione) with increased catalase activity (CAT) at all post treatment 
follow up intervals. Lipid peroxidation significantly increased at all the autopsy intervals. The protein content of the ain 
depleted upto 7th day after microwave exposure Radial arm maze test revealed that 10 GHz leads to significant depletion 
in spatial learning and memory performance in Swiss albino mice. Free radicals causing oxidative stress may be responsible 
for altered biochemical levels of the ain and impairment of learning and working memory of Swiss albino mice after microwave exposure.

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Archana Sharma, Deepak Bhatnagar, Rashmi Sisodia 10 Ghz Microwaves Induced Biochemical, Learning and Memory Alterations in Swiss Albino Mice Brain Indian Journal of Applied Research, Vol.4, Issue : 5 May 2014


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