IJSR - International Journal of Scientific Research

Dr. Jaidev Singh; Saman Amin; Dr. Rajesh Kumar

Volume : VIII, Issue : VIII, August - 2019

A CASE CONTROL STUDY OF LIPID PROFILE AND SERUM URIC ACID LEVELS IN PATIENTS OF CARDIOVASCULAR HYPERTENSION

Dr. Jaidev Singh, Saman Amin, Dr. Rajesh Kumar

Abstract :

Background: Hypertension is a major public health problem which is major risk factor for chronic heart disease, stroke, and coronary heart disease. Hypertension and increased blood levels of triglyceride (TG), total cholesterol (TC), and low–density lipoprotein (LDL) has a widely accepted association. The debate on the association between uric acid and hypertension, controversy still remains. Material and Method: The study was carried out on 75 subjects of hypertensive patients, and 72 controls. In the study we have investigated changes in biochemical parameters in people suffering from hypertension and compare these values with that normal subjects. Healthy volunteers of 40–60 years who were not suffering from hypertension were selected randomly as controls from the hospital and college. Results: Most of the patients in both of the groups were in young to middle age group. Cholesterol, TG, VLDL and uric acid was elevated in hypertensive group significantly (P<0.0001), while HDL and LDL levels were not significantly different between the two groups. Conclusion: Significantly raised cholesterol, triglyceride, VLDL levels are associated with hypertension while HDL and LDL levels show no statistical association. Serum Uric acid levels are also significantly high in hypertensive patients than normotensive controls