A CLINICOPATHOLOGICAL STUDY OF SINONASAL MASSES WITH MAST CELL DENSITY- A SERIES OF 130 CASES.

DR.ABHISHEK SHARMA; DR.RANU ROY BISWAS; Dr CHHANDA DATTA; DR.MANOTOSH DUTTA

Volume : VIII, Issue : I, January - 2019

A CLINICOPATHOLOGICAL STUDY OF SINONASAL MASSES WITH MAST CELL DENSITY- A SERIES OF 130 CASES.

Dr. Abhishek Sharma, Dr. Ranu Roy Biswas, Dr Chhanda Datta, Dr. Manotosh Dutta

Abstract :

Although the nasal cavity and paranasal sinuses occupy a relatively small anatomical space, they are the site of origin of some of the more complex, histologically diverse group of tumors in the entire human body. Inflammatory polyps are the commonest lesions. 130 cases of sinonasal mass for a period of two years were studied. 1% Toluidine blue stain for mast cell was done and the same was counted and expressed both in sqmm and per HPF.

We found that Mast cell density was more in benign lesions (61.9�17.9/sq mm) than malignant lesions (6.3/sq mm). Among the malignant lesion more aggressive tumors like alveolar rhabdomyosarcoma and small cell CA had lower mast cell density than that of PLGA. Inflammatory nasal polyp having history of allergy had severe eosinophilic infiltration.