A Comparative Biochemical Evaluation of Serum  C– Reactive Protein (CRP) and Erythrocyte  Sedimentation Rate (ESR) in Healthy Individuals  and Patients Having Odontogenic Infections

Dr Jayprasad N Shetty; Dr Pratik D Shah

Volume : II, Issue : XII, December - 2013

A Comparative Biochemical Evaluation of Serum C– Reactive Protein (CRP) and Erythrocyte Sedimentation Rate (ESR) in Healthy Individuals and Patients Having Odontogenic Infections

Dr Jayprasad N Shetty, Dr Pratik D Shah

Abstract :

Aims & Objectives -To assess the efficacy of serum C - reactive protein and Erythrocyte sedimentation rate levels as monitoring tool for patients with facial space infections of odontogenic origin for determining severity of infection, to assess therapeutic efficacy of different treatment regime and to assess the recovery process during disease period. Materials and Methods: Thirty patients with facial space infections of odontogenic origin were enrolled in the study to evaluate level of serum CRP and ESR at the time of diagnosis and 1 week post operatively. The level of serum CRP and ESR were also assessed in 25 healthy individuals in control group. Serum CRP was measured by qualitative and semi quantitative, latex agglutination method. ESR was measured by Westergren method. Then results were compared. Results: There was a rapid rise and fall of CRP compared to ESR which indicates CRP is much more sensitive indicator for infection and inflammation compared to ESR. Conclusion - Incorporating CRP test in management of odontogenic facial infections help in stopping antibiotics safely, sp� patients from drug toxicity, probably decreasing the emergence of resistance and decreasing costs.