A comparative study of bupivacaine,bupivacaine  with dexmedetomidine and bupivacaine  with clonidine in spinal anesthesia for lower  abdominal surgery

Dr. Charu J. Pandya; Dr Chirag G. Baranda; Dr. Shivang C. Joshi

Volume : II, Issue : VII, July - 2013

A comparative study of bupivacaine,bupivacaine with dexmedetomidine and bupivacaine with clonidine in spinal anesthesia for lower abdominal surgery

Dr. Charu J. Pandya, Dr Chirag G. Baranda, Dr. Shivang C. Joshi

Abstract :

The present clinical comparative study was carried out in 90 patients of ASA GRADE I and II scheduled for lower abdominal surgery. They were divided into three groups of 30 each. The patients in group A received Bupivacaine alone and Patient in group B received Bupivacaine + dexmedetomidine and group c received bupivacaine + clonidine intrathecaly. Total drug volume with saline in both the groups was 3.5 ml. In our study we have found out that when clonidine/dexmedetomidine added to bupivacaine, prolongs the time of onset for sensory and motor block, Quality of central neuraxial block is good. Motor block achieved is complete, duration of central neuraxial block is increased and effective analgesia increases considerably. Hemodynamic stability were maintained, didn�t produce excessive sedation. However these effects were more pronounced with clonidine than dexmedetomidine. So we concluded that clonidine as an adjuvant to bupivacaine to produce CNB is better in prolonging the duration of spinal analgesia and postoperative analgesia with hemodynamic stability without any significant side effects.