Volume : VII, Issue : III, March - 2018

A COMPARATIVE STUDY OF THE EFFECT OF CAUDAL VS INTRAVENOUS CLONIDINE ON POST OPERATIVE ANALGESIA PRODUCED BY CAUDAL LEVOBUPIVACAINE IN CHILDREN UNDER GOING SUBUMBLICAL SURGERIES.

Rajni Mathur, Pratibha Rathore, Divya Gaur

Abstract :

 Aims & Objectives: To assess and compare duration of analgesia, hemodynamic changes, adverse effects of caudal v/s intravenous clonidine on postoperative analgesia produced by caudal levobupivacaine.

Methods: After approval from the ethical committee a randomized, double blind, controlled type study of 90 children of ASA I/II, aged  between 2  to 8 years, posted for subumbilical surgeries under caudal block were taken and randomly allocated in three groups.

·         Group A (L)(n=30) – received levobupivacaine 0.25% (0.75 ml/kg ) and 5ml normal saline IV.

·         Group B (LCcau) (n=30)– received levobupivacaine 0.25% (0.75 ml/kg) and 2µg/kg clonidine caudally and 5ml normal saline IV.

·         Group C (LCiv) (n=30)– received levobupivacaine 0.25% (0.75ml/kg) caudally and 2µg/kg clonidine and normal saline making total volume of 5ml IV.

Results: There was no significant difference in the duration of surgery in all three groups (40±16.1 min in group L, 44±19.4min in group LCcau and 45.5±19.4 min in group LCiv). The CHIPPS scores for assessment of post operative pain were significantly higher in patients of group L as compared to group LCcau and LCiv.  . The mean duration of post operative analgesia was (342.8±110.6min in group L, 461.4±125.6min in group LCiv and 671.3±82.3min in group LCcau.) ( P<0.01)  The mean sedation scores in all the three groups were comparable (P value between groups >0.5) and no motor block was observed in all the three groups. The mean rescue analgesia was highest in group L (1.4±0.6) significantly less rescue analgesics required in the group LCcau as compared to group LCiv (0.1±0.3 v/s 0.9±0.3)( p=<0.05).

Conclusion: Addition of clonidine (2µg/kg) as an adjuvant to caudal levobupivacaine has long lasting post operative analgesia and less no. of rescue analgesics requirement without additional side effects as compared to intravenous clonidine with caudal levobupivacaine

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Rajni Mathur, Pratibha Rathore, Divya Gaur, A COMPARATIVE STUDY OF THE EFFECT OF CAUDAL VS INTRAVENOUS CLONIDINE ON POST OPERATIVE ANALGESIA PRODUCED BY CAUDAL LEVOBUPIVACAINE IN CHILDREN UNDER GOING SUBUMBLICAL SURGERIES., INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-3 | March-2018


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