IJSR - International Journal of Scientific Research

Dr. Himanshukumar V. Patel; Dr. Chandani Shah; Dr. Meemansha Buch; Dr. J.R. Khambholja; Dr. P.N. Palat

Volume : VI, Issue : IX, September - 2017

A establishments of relationship between Parathyroid Adenoma and Pathological Fracture (Incidental)

Dr. Himanshukumar V. Patel, Dr. Chandani Shah, Dr. Meemansha Buch, Dr. J. R. Khambholja, Dr. P. N. Palat

Abstract :

Parathyroid Adenoma is the common cause of primary hyperparathyrodism present with mostly asymptomatic Hypercalcemia. In present case report we describe a case of Adenoma with Hypercalcemia and Pathological Fracture.

– Parathyroid Adenoma lead to excessive secretion of PTH (Parathyroid Hormone).

– PTH is 84 Amino acid single chain peptide

It act by maintain the Ca–Homeostatic mechanism by – direct action on the Bone and Kidney.

– By ↑ Catt & ↓ Phosphate & Indirectly ◦action–↑ Vitamin – D

In case of Parathyroid Adenoma ↑↑ PTH → lead to bone resorption & release calcium & Phosphate excretion – ↓ Bone Density & Hyaercalcemia ↑ incidence of Pathological Fracture