Volume : V, Issue : VI, June - 2016

A Predictor of Neonatal Outcome Umbilical Cord Blood Nucleated RBCs.

Pendurthi Venkata Krishna, Abhishek Mahankali V

Abstract :

 BACKGROUND AND OBJECTIVES 1. To compare nucleated red blood cells (NRBC) count in the umbilical cord blood of normal term newborns, of mothers with pregnancy induced hypertension and preterm newborns who were delivered spontaneously without any risk factors. 2. NRBC count and its relation to immediate neonatal outcome. METHODOLOGY Peripheral smear was prepared from the umbilical cord blood of 150 newborns born in Shadan Hospital, Hyderabad. The study included 50 term babies, 50 spontaneously delivered preterm babies, and 50 babies of mothers having pregnancy induced hypertension. Basic data of mothers like age, parity, haemoglobin level, diabetes, pregnancy induced hypertension and foetal presentation were collected. Also natal risk factors like prolonged second stage, mode of delivery and presence of meconium stained amniotic fluid were documented. Babies were examined soon after birth and preliminary data regarding the babies were also noted. Immediately after delivery umbilical cord is double clamped and cord blood was obtained. Peripheral smear was prepared soon after, stained with Leishmans stain. The number of NRBC was studied in prepared slides. These babies were followed up till discharge and data regarding morbidity and mortality were also documented. RESULTS Normal values of NRBC in normal term babies were found to be 3.54+1.05 in the present study. It was also found that NRBC are significantly increased in preterm babies (6.54+4.74) followed by newborns of mothers with PIH (6.42+3.08). Significant association was found between Apgar at 1 minute (P=0.016), respiratory distress (P=0.002) and elevated NRBC in preterm babies. No significant association was found between age of mother, parity, blood group of mother, Apgar at 5 minutes, intrauterine growth retardation, maternal anaemia and elevated NRBC. CONCLUSION NRBC can be used as a marker of intrauterine hypoxia and it is significantly associated with bad outcome in terms of morbidity and mortality. This test is quick, reliable, cost effective and easy to do. So it can be used as a bedside test to predict early neonatal outcome.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Pendurthi Venkata Krishna, Abhishek Mahankali V A Predictor of Neonatal Outcome Umbilical Cord Blood Nucleated RBCs. International Journal of Scientific Research, Vol : 5, Issue : 6 JUNE 2016

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